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Corticostriatal dysfunction and glutamate transporter 1 (GLT1) in Huntington’s disease: interactions between neurons and astrocytes

Huntington’s Disease (HD) is a fatally inherited neurodegenerative disorder caused by an expanded glutamine repeat in the N-terminal region of the huntingtin (HTT) protein. The result is a progressively worsening triad of cognitive, emotional, and motor alterations that typically begin in adulthood...

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Autors principals: Estrada-Sánchez, Ana María, Rebec, George V.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418680/
https://ncbi.nlm.nih.gov/pubmed/22905336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.baga.2012.04.029
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