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Corticostriatal network dysfunction in Huntington's disease: Deficits in neural processing, glutamate transport, and ascorbate release

AIMS: This review summarizes evidence for dysfunctional connectivity between cortical and striatal neurons in Huntington's disease (HD), a fatal neurodegenerative condition caused by a single gene mutation. The focus is on data derived from recording of electrophysiological signals in behaving...

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Pubblicato in:CNS Neurosci Ther
Autore principale: Rebec, George V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489880/
https://ncbi.nlm.nih.gov/pubmed/29464896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12828
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