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Corticostriatal dysfunction underlies diminished striatal ascorbate release in the R6/2 mouse model of Huntington’s disease

A behavior-related deficit in the release of ascorbate (AA), an antioxidant vitamin, occurs in the striatum of R6/2 mice expressing the human mutation for Huntington’s disease (HD), a dominantly inherited condition characterized by striatal dysfunction. To determine the role of corticostriatal fiber...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Dorner, Jenelle L., Miller, Benjamin R., Klein, Emma L., Murphy-Nakhnikian, Alexander, Andrews, Rachel L., Barton, Scott J., Rebec, George V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745264/
https://ncbi.nlm.nih.gov/pubmed/19616518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.07.019
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