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A novel motif in telomerase reverse transcriptase regulates telomere repeat addition rate and processivity
Telomerase is a specialized reverse transcriptase that adds telomeric DNA repeats onto chromosome termini. Here, we characterize a new telomerase-specific motif, called motif 3, in the catalytic domain of telomerase reverse transcriptase, that is crucial for telomerase function and evolutionally con...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2847249/ https://ncbi.nlm.nih.gov/pubmed/20044353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1198 |
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