Telomerase reverse transcriptase and telomeric-repeat binding factor protein 1 as regulators of telomerase activity in pancreatic cancer cells

Telomerase adds hexameric repeats of 5′-TTAGGG-3′ termed telomeres to ends of chromosomal DNA. This enzyme has been implicated in cellular immortalization and cellular senescence. Recently, a number of relevant genes have been cloned, including these encoding three major components of human telomera...

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Autori principali: Yajima, T, Yagihashi, A, Kameshima, H, Kobayashi, D, Hirata, K, Watanabe, N
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2001
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Regular Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364122/
https://ncbi.nlm.nih.gov/pubmed/11531263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1954
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