A Conserved Telomerase Motif within the Catalytic Domain of Telomerase Reverse Transcriptase Is Specifically Required for Repeat Addition Processivity

Telomerase is a ribonucleoprotein reverse transcriptase responsible for the maintenance of one strand of the telomere terminal repeats. The catalytic protein subunit of the telomerase complex, known as TERT, possesses a reverse transcriptase (RT) domain that mediates nucleotide addition. The RT doma...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Lue, Neal F., Lin, You-Chin, Mian, I. Saira
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2003
Sujets:
DNA Dynamics and Chromosome Structure
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262686/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14612390/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.23.8440-8449.2003
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