A Conserved Telomerase Motif within the Catalytic Domain of Telomerase Reverse Transcriptase Is Specifically Required for Repeat Addition Processivity

Telomerase is a ribonucleoprotein reverse transcriptase responsible for the maintenance of one strand of the telomere terminal repeats. The catalytic protein subunit of the telomerase complex, known as TERT, possesses a reverse transcriptase (RT) domain that mediates nucleotide addition. The RT doma...

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Detalhes bibliográficos
Main Authors: Lue, Neal F., Lin, You-Chin, Mian, I. Saira
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
DNA Dynamics and Chromosome Structure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC262686/
https://ncbi.nlm.nih.gov/pubmed/14612390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.23.8440-8449.2003
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