A Conserved Telomerase Motif within the Catalytic Domain of Telomerase Reverse Transcriptase Is Specifically Required for Repeat Addition Processivity

Telomerase is a ribonucleoprotein reverse transcriptase responsible for the maintenance of one strand of the telomere terminal repeats. The catalytic protein subunit of the telomerase complex, known as TERT, possesses a reverse transcriptase (RT) domain that mediates nucleotide addition. The RT doma...

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Bibliographic Details

Published in:	Mol Cell Biol
Main Authors:	Lue, Neal F., Lin, You-Chin, Mian, I. Saira
Format:	Artigo
Language:	Inglês
Published:	Taylor & Francis 2003
Subjects:	DNA Dynamics and Chromosome Structure
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262686/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14612390/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.23.8440-8449.2003
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