The epidermal growth factor tyrosine kinase inhibitor AG1478 and erlotinib reverse ABCG2-mediated drug resistance

ABCG2 is an important member of ATP-binding cassette (ABC) transporter shown to confer drug resistance in cancer cells. Recent studies show that an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), gefitinib, is able to modulate the function of ABCG2 and reverse ABCG2-mediated...

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Huvudupphovsmän: Shi, Zhi, Parmar, Smitaben, Peng, Xing-Xiang, Shen, Tong, Robey, Robert W., Bates, Susan E., Fu, Li-Wu, Shao, Yining, Chen, Yang-Min, Zang, Feiyang, Chen, Zhe-Sheng
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845641/
https://ncbi.nlm.nih.gov/pubmed/19148526
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