Olmutinib (BI1482694/HM61713), a Novel Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Reverses ABCG2-Mediated Multidrug Resistance in Cancer Cells

The main characteristic of tumor cell resistance is multidrug resistance (MDR). MDR is the principle cause of the decline in clinical efficacy of chemotherapeutic drugs. There are several mechanisms that could cause MDR. Among these, one of the most important mechanisms underlying MDR is the overexp...

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發表在:Front Pharmacol
Main Authors: Zhang, Wei, Fan, Ying-Fang, Cai, Chao-Yun, Wang, Jing-Quan, Teng, Qiu-Xu, Lei, Zi-Ning, Zeng, Leli, Gupta, Pranav, Chen, Zhe-Sheng
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2018
主題:
Pharmacology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189370/
https://ncbi.nlm.nih.gov/pubmed/30356705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01097
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