Olmutinib (HM61713) reversed multidrug resistance by inhibiting the activity of ATP-binding cassette subfamily G member 2 in vitro and in vivo

Overexpressing of ATP-binding cassette (ABC) transporters is the essential cause of multidrug resistance (MDR), which is a significant hurdle to the success of chemotherapy in many cancers. Therefore, inhibiting the activity of ABC transporters may be a logical approach to circumvent MDR. Olmutinib...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Acta Pharm Sin B
Main Authors: Zhang, Zhiqiang, Guo, Xiaoran, To, Kenneth K.W., Chen, Zhen, Fang, Xiaona, Luo, Min, Ma, Chunling, Xu, Jianhua, Yan, Shirong, Fu, Liwu
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089862/
https://ncbi.nlm.nih.gov/pubmed/30109181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2018.06.002
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker