The Arf tumor suppressor protein inhibits Miz1 to suppress cell adhesion and induce apoptosis

Oncogenic stress induces expression of the alternate reading frame (Arf) tumor suppressor protein. Arf then stabilizes p53, which leads to cell cycle arrest or apoptosis. The mechanisms that distinguish both outcomes are incompletely understood. In this study, we show that Arf interacts with the Myc...

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Main Authors: Herkert, Barbara, Dwertmann, Anne, Herold, Steffi, Abed, Mona, Naud, Jean-Francois, Finkernagel, Florian, Harms, Gregory S., Orian, Amir, Wanzel, Michael, Eilers, Martin
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2010
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845071/
https://ncbi.nlm.nih.gov/pubmed/20308430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200908103
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