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The Arf tumor suppressor protein inhibits Miz1 to suppress cell adhesion and induce apoptosis
Oncogenic stress induces expression of the alternate reading frame (Arf) tumor suppressor protein. Arf then stabilizes p53, which leads to cell cycle arrest or apoptosis. The mechanisms that distinguish both outcomes are incompletely understood. In this study, we show that Arf interacts with the Myc...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2845071/ https://ncbi.nlm.nih.gov/pubmed/20308430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200908103 |
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