The Arf tumor suppressor protein inhibits Miz1 to suppress cell adhesion and induce apoptosis

Oncogenic stress induces expression of the alternate reading frame (Arf) tumor suppressor protein. Arf then stabilizes p53, which leads to cell cycle arrest or apoptosis. The mechanisms that distinguish both outcomes are incompletely understood. In this study, we show that Arf interacts with the Myc...

Full description

Saved in:
Bibliographic Details
Main Authors: Herkert, Barbara, Dwertmann, Anne, Herold, Steffi, Abed, Mona, Naud, Jean-Francois, Finkernagel, Florian, Harms, Gregory S., Orian, Amir, Wanzel, Michael, Eilers, Martin
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2010
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845071/
https://ncbi.nlm.nih.gov/pubmed/20308430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200908103
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items