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The Cytosolic Domain of Bcl-2 Forms Small Pores on Model Mitochondrial Outer Membrane After Acidic pH-Induced Membrane Association
The permeability of mitochondrial outer membrane (MOM) is regulated by proteins of the Bcl-2 family via their interactions at the membrane. While pro-apoptotic Bax protein promotes MOM permeabilization (MOMP) releasing cytochrome c after activation by BH3-only protein, anti-apoptotic Bcl-2 protein p...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2844873/ https://ncbi.nlm.nih.gov/pubmed/19334571 |
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