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The Bax BH3 Peptide H2–H3 Promotes Apoptosis by Inhibiting Bcl-2’s Pore-Forming and Anti-Bax Activities in the Membrane

Pore-formation and protein-protein interactions are considered to play critical roles in the regulation of apoptosis by Bcl-2 family proteins. During the initiation of apoptosis, the anti-apoptotic Bcl-2 and the pro-apoptotic Bax form different pores to regulate the permeability of mitochondrial out...

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Autori principali: Peng, Jun, Lapolla, Suzanne M., Zhang, Zhi, Lin, Jialing
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844869/
https://ncbi.nlm.nih.gov/pubmed/19813621
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