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The Bax BH3 Peptide H2–H3 Promotes Apoptosis by Inhibiting Bcl-2’s Pore-Forming and Anti-Bax Activities in the Membrane
Pore-formation and protein-protein interactions are considered to play critical roles in the regulation of apoptosis by Bcl-2 family proteins. During the initiation of apoptosis, the anti-apoptotic Bcl-2 and the pro-apoptotic Bax form different pores to regulate the permeability of mitochondrial out...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2844869/ https://ncbi.nlm.nih.gov/pubmed/19813621 |
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