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AUTO-ACTIVATION OF THE APOPTOSIS PROTEIN BAX INCREASES MITOCHONDRIAL MEMBRANE PERMEABILITY AND IS INHIBITED BY BCL-2

Interactions among Bcl-2 family proteins mediated by Bcl-2 homology (BH) regions transform apoptosis signals into actions. The interactions between BH3 region-only proteins and multi-BH region proteins such as Bax and Bcl-2 have been proposed to be the dominant interactions required for initiating a...

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Detalhes bibliográficos
Main Authors: Tan, Chibing, Dlugosz, Paulina J., Peng, Jun, Zhang, Zhi, Lapolla, Suzanne M., Plafker, Scott M., Andrews, David W., Lin, Jialing
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826894/
https://ncbi.nlm.nih.gov/pubmed/16571718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M602374200
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