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Biophysical Investigation of GpIbα Binding to Thrombin Anion Binding Exosite II
Substrates and cofactors of the serine protease thrombin (IIa) employ two anion binding exosites (ABE-I and II) to aid in binding. On the surface of platelets resides the membrane bound receptor complex GpIbα/β-GpIX-GpV. IIa’s ABE-II is proposed to interact with an anionic portion of GpIbα which enh...
Gorde:
| Egile Nagusiak: | , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2009
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2842903/ https://ncbi.nlm.nih.gov/pubmed/19591434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900745b |
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