Partial hexokinase II knockout results in acute ischemia–reperfusion damage in skeletal muscle of male, but not female, mice

Cellular studies have demonstrated a protective role of mitochondrial hexokinase against oxidative insults. It is unknown whether HK protective effects translate to the in vivo condition. In the present study, we hypothesize that HK affects acute ischemia–reperfusion injury in skeletal muscle of the...

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Detalhes bibliográficos
Main Authors: Smeele, Kirsten M., Eerbeek, Otto, Koeman, Anneke, Bezemer, Rick, Ince, Can, Heikkinen, Sami, Laakso, Markku, de Haan, Arnold, Schaart, Gert, Drost, Maarten R., Hollmann, Markus W., Zuurbier, Coert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
Assuntos:
Molecular and Genomic Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842566/
https://ncbi.nlm.nih.gov/pubmed/20182739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-010-0787-3
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