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Cyclophilin D ablation is associated with increased end-ischemic mitochondrial hexokinase activity
Both the absence of cyclophilin D (CypD) and the presence of mitochondrial bound hexokinase II (mtHKII) protect the heart against ischemia/reperfusion (I/R) injury. It is unknown whether CypD determines the amount of mtHKII in the heart. We examined whether CypD affects mtHK in normoxic, ischemic an...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5630626/ https://ncbi.nlm.nih.gov/pubmed/28986541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13096-7 |
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