Partial hexokinase II knockout results in acute ischemia–reperfusion damage in skeletal muscle of male, but not female, mice

Cellular studies have demonstrated a protective role of mitochondrial hexokinase against oxidative insults. It is unknown whether HK protective effects translate to the in vivo condition. In the present study, we hypothesize that HK affects acute ischemia–reperfusion injury in skeletal muscle of the...

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Hauptverfasser: Smeele, Kirsten M., Eerbeek, Otto, Koeman, Anneke, Bezemer, Rick, Ince, Can, Heikkinen, Sami, Laakso, Markku, de Haan, Arnold, Schaart, Gert, Drost, Maarten R., Hollmann, Markus W., Zuurbier, Coert J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer-Verlag 2010
Schlagworte:
Molecular and Genomic Physiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842566/
https://ncbi.nlm.nih.gov/pubmed/20182739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-010-0787-3
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