Deletion of the Innate Immune NLRP3 Receptor Abolishes Cardiac Ischemic Preconditioning and Is Associated with Decreased Il-6/STAT3 Signaling

OBJECTIVE: Recent studies indicate that the innate immune system is not only triggered by exogenous pathogens and pollutants, but also by endogenous danger signals released during ischemia and necrosis. As triggers for the innate immune NLRP3 inflammasome protein complex appear to overlap with those...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zuurbier, Coert J., Jong, Willeke M. C., Eerbeek, Otto, Koeman, Anneke, Pulskens, Wilco P., Butter, Loes M., Leemans, Jaklien C., Hollmann, Markus W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407219/
https://ncbi.nlm.nih.gov/pubmed/22848390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040643
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