Nlrp3 Prevents Early Renal Interstitial Edema and Vascular Permeability in Unilateral Ureteral Obstruction

Progressive renal disease is characterized by tubulo-interstitial injury with ongoing inflammation and fibrosis. The Nlrp3 inflammasome contributes to these pathophysiological processes through its canonical effects in cytokine maturation. Nlrp3 may additionally exert inflammasome-independent effect...

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Autori principali: Pulskens, Wilco P., Butter, Loes M., Teske, Gwendoline J., Claessen, Nike, Dessing, Mark C., Flavell, Richard A., Sutterwala, Fayyaz S., Florquin, Sandrine, Leemans, Jaklien C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893260/
https://ncbi.nlm.nih.gov/pubmed/24454932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085775
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