A Tissue-Specific Role for Nlrp3 in Tubular Epithelial Repair after Renal Ischemia/Reperfusion

Ischemia/reperfusion injury is a major cause of acute kidney injury. Improving renal repair would represent a therapeutic strategy to prevent renal dysfunction. The innate immune receptor Nlrp3 is involved in tissue injury, inflammation, and fibrosis; however, its role in repair after ischemia/reper...

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Veröffentlicht in:Am J Pathol
Hauptverfasser: Bakker, Pieter J., Butter, Loes M., Claessen, Nike, Teske, Gwendoline J.D., Sutterwala, Fayyaz S., Florquin, Sandrine, Leemans, Jaklien C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707188/
https://ncbi.nlm.nih.gov/pubmed/24823805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.04.005
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