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Blood pressure influences end-stage renal disease of Cd151 knockout mice

Podocytes of the kidney adhere tightly to the underlying glomerular basement membrane (GBM) in order to maintain a functional filtration barrier. The clinical importance of podocyte binding to the GBM via an integrin-laminin-actin axis has been illustrated in models with altered function of α3β1 int...

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Détails bibliographiques
Auteurs principaux: Sachs, Norman, Claessen, Nike, Aten, Jan, Kreft, Maaike, Teske, Gwendoline J.D., Koeman, Anneke, Zuurbier, Coert J., Janssen, Hans, Sonnenberg, Arnoud
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248294/
https://ncbi.nlm.nih.gov/pubmed/22201679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI58878
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