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Diminished Aβ Burden in Tg2576 Mice Following a Prophylactic Oral Immunization with a Salmonella-based Aβ Derivative Vaccine

Immunotherapy holds great promise for Alzheimer's disease (AD) and other conformational disorders but certain adverse reactions need to be overcome. Prior to the side effects in the first Elan/Wyeth AD vaccine trial, we proposed using amyloid-β (Aβ) derivatives as a safer approach. The route of...

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Detalhes bibliográficos
Main Authors: Boutajangout, Allal, Goni, Fernando, Knudsen, Elin, Schreiber, Fernanda, Asuni, Ayodeji, Quartermain, David, Frangione, Blas, Chabalgoity, Alejandro, Wisniewski, Thomas, Sigurdsson, Einar M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842483/
https://ncbi.nlm.nih.gov/pubmed/19749432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2009-1204
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