Antibody response and plasma Aβ1-40 levels in young Microcebus murinus primates immunized with Aβ1-42 and its derivatives

We have been developing Aβ derivative vaccines with the objective to improve the safety of Aβ targeting immunotherapy. Our Aβ homologs are designed to have less direct toxicity and to produce a modified immune response compared to Aβ. In extensive mouse studies, all our vaccines have improved cognit...

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Hlavní autoři: Trouche, Stéphanie G., Asuni, Ayodeji, Rouland, Sylvie, Wisniewski, Thomas, Frangione, Blas, Verdier, Jean-Michel, Sigurdsson, Einar M., Mestre-Francés, Nadine
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713060/
https://ncbi.nlm.nih.gov/pubmed/19114076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.12.012
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