Vaccination of Alzheimer’s model mice with Aβ derivative in alum adjuvant reduces Aβ burden without microhemorrhages

Immunotherapy holds great promise for Alzheimer’s disease (AD) and other conformational disorders but certain adverse reactions need to be overcome. The meningoencephalitis observed in the first AD vaccination trial was likely related to excessive cell-mediated immunity caused by the immunogen, amyl...

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Main Authors: Asuni, Ayodeji A., Boutajangout, Allal, Scholtzova, Henrieta, Knudsen, Elin, Li, Yong Sheng, Quartermain, David, Frangione, Blas, Wisniewski, Thomas, Sigurdsson, Einar M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779823/
https://ncbi.nlm.nih.gov/pubmed/17100841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2006.05149.x
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