Allele-specific tumor spectrum in Pten knockin mice

Germline mutations in the tumor suppressor gene PTEN (phosphatase and tensin homology deleted on chromosome 10) cause Cowden and Bannayan–Riley–Ruvalcaba (BRR) syndromes, two dominantly inherited disorders characterized by mental retardation, multiple hamartomas, and variable cancer risk. Here, we m...

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Detaylı Bibliyografya
Asıl Yazarlar: Wang, Hui, Karikomi, Matt, Naidu, Shan, Rajmohan, Ravi, Caserta, Enrico, Chen, Hui-Zi, Rawahneh, Maysoon, Moffitt, Julie, Stephens, Julie A., Fernandez, Soledad A., Weinstein, Michael, Wang, Danxin, Sadee, Wolfgang, La Perle, Krista, Stromberg, Paul, Rosol, Thomas J., Eng, Charis, Ostrowski, Michael C., Leone, Gustavo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2010
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841921/
https://ncbi.nlm.nih.gov/pubmed/20194734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912524107
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