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Pten in the Breast Tumor Microenvironment: Modeling Tumor-Stroma Co-Evolution

Solid human tumors and their surrounding microenvironment are hypothesized to co-evolve in a manner that promotes tumor growth, invasiveness and spread. Mouse models of cancer have focused on genetic changes in the epithelial tumor cells and therefore have not robustly tested this hypothesis. We hav...

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Detalhes bibliográficos
Main Authors: Wallace, Julie A., Li, Fu, Leone, Gustavo, Ostrowski, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075554/
https://ncbi.nlm.nih.gov/pubmed/21303970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3263
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