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Evolution of Tumor Invasiveness: The Adaptive Tumor Microenvironment Landscape Model

Interactions between cancer cells and their microenvironment are crucial for promoting tumor growth and invasiveness. In the tumor adaptive landscape model, hypoxic and acidic microenvironmental conditions reduce the fitness of cancer cells and significantly restrict their proliferation. This select...

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Podrobná bibliografie
Hlavní autoři: Lee, Hyung-Ok, Silva, Ariosto S., Concilio, Susanna, Li, Yue-Sheng, Slifker, Michael, Gatenby, Robert A., Cheng, Jonathan D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197231/
https://ncbi.nlm.nih.gov/pubmed/21859828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-0304
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