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A theoretical quantitative model for evolution of cancer chemotherapy resistance

BACKGROUND: Disseminated cancer remains a nearly uniformly fatal disease. While a number of effective chemotherapies are available, tumors inevitably evolve resistance to these drugs ultimately resulting in treatment failure and cancer progression. Causes for chemotherapy failure in cancer treatment...

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Detalhes bibliográficos
Main Authors: Silva, Ariosto S, Gatenby, Robert A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868834/
https://ncbi.nlm.nih.gov/pubmed/20406443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-5-25
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