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A theoretical quantitative model for evolution of cancer chemotherapy resistance

BACKGROUND: Disseminated cancer remains a nearly uniformly fatal disease. While a number of effective chemotherapies are available, tumors inevitably evolve resistance to these drugs ultimately resulting in treatment failure and cancer progression. Causes for chemotherapy failure in cancer treatment...

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Hlavní autoři: Silva, Ariosto S, Gatenby, Robert A
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868834/
https://ncbi.nlm.nih.gov/pubmed/20406443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-5-25
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