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Adaptation to Survival in Germinal Center is the Initial Step in Onset of Indolent Stage of Multiple Myeloma
Aberrant mutations of centrocytes in germinal centers (GC) can generate two completely different diseases: B-cell lymphomas and monoclonal gammopathy of undetermined significance (MGUS). In this article we use computational models to examine the evolutionary dynamics by which initial adaptation to s...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3437606/ https://ncbi.nlm.nih.gov/pubmed/21958215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp200279p |
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