Timing the initiation of multiple myeloma

The evolution and progression of multiple myeloma and its precursors over time is poorly understood. Here, we investigate the landscape and timing of mutational processes shaping multiple myeloma evolution in a large cohort of 89 whole genomes and 973 exomes. We identify eight processes, including a...

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Publicado no:Nat Commun
Main Authors: Rustad, Even H., Yellapantula, Venkata, Leongamornlert, Daniel, Bolli, Niccolò, Ledergor, Guy, Nadeu, Ferran, Angelopoulos, Nicos, Dawson, Kevin J., Mitchell, Thomas J., Osborne, Robert J., Ziccheddu, Bachisio, Carniti, Cristiana, Montefusco, Vittorio, Corradini, Paolo, Anderson, Kenneth C., Moreau, Philippe, Papaemmanuil, Elli, Alexandrov, Ludmil B., Puente, Xose S., Campo, Elias, Siebert, Reiner, Avet-Loiseau, Herve, Landgren, Ola, Munshi, Nikhil, Campbell, Peter J., Maura, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174344/
https://ncbi.nlm.nih.gov/pubmed/32317634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15740-9
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