Timing the initiation of multiple myeloma

The evolution and progression of multiple myeloma and its precursors over time is poorly understood. Here, we investigate the landscape and timing of mutational processes shaping multiple myeloma evolution in a large cohort of 89 whole genomes and 973 exomes. We identify eight processes, including a...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Rustad, Even H., Yellapantula, Venkata, Leongamornlert, Daniel, Bolli, Niccolò, Ledergor, Guy, Nadeu, Ferran, Angelopoulos, Nicos, Dawson, Kevin J., Mitchell, Thomas J., Osborne, Robert J., Ziccheddu, Bachisio, Carniti, Cristiana, Montefusco, Vittorio, Corradini, Paolo, Anderson, Kenneth C., Moreau, Philippe, Papaemmanuil, Elli, Alexandrov, Ludmil B., Puente, Xose S., Campo, Elias, Siebert, Reiner, Avet-Loiseau, Herve, Landgren, Ola, Munshi, Nikhil, Campbell, Peter J., Maura, Francesco
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174344/
https://ncbi.nlm.nih.gov/pubmed/32317634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15740-9
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