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mmsig: a fitting approach to accurately identify somatic mutational signatures in hematological malignancies

Mutational signatures have emerged as powerful biomarkers in cancer patients, with prognostic and therapeutic implications. Wider clinical utility requires access to reproducible algorithms, which allow characterization of mutational signatures in a given tumor sample. Here, we show how mutational s...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Rustad, Even H., Nadeu, Ferran, Angelopoulos, Nicos, Ziccheddu, Bachisio, Bolli, Niccolò, Puente, Xose S., Campo, Elias, Landgren, Ola, Maura, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007623/
https://ncbi.nlm.nih.gov/pubmed/33782531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01938-0
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