Revealing the Impact of Structural Variants in Multiple Myeloma

The landscape of structural variants (SV) in multiple myeloma remains poorly understood. Here, we performed comprehensive analysis of SVs in a large cohort of 752 patients with multiple myeloma by low-coverage long-insert whole-genome sequencing. We identified 68 SV hotspots involving 17 new candida...

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Detalhes bibliográficos
Publicado no:Blood Cancer Discov
Main Authors: Rustad, Even H., Yellapantula, Venkata D., Glodzik, Dominik, Maclachlan, Kylee H., Diamond, Benjamin, Boyle, Eileen M., Ashby, Cody, Blaney, Patrick, Gundem, Gunes, Hultcrantz, Malin, Leongamornlert, Daniel, Angelopoulos, Nicos, Agnelli, Luca, Auclair, Daniel, Zhang, Yanming, Dogan, Ahmet, Bolli, Niccolò, Papaemmanuil, Elli, Anderson, Kenneth C., Moreau, Philippe, Avet-Loiseau, Hervé, Munshi, Nikhil C., Keats, Jonathan J., Campbell, Peter J., Morgan, Gareth J., Landgren, Ola, Maura, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for Cancer Research 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7774871/
https://ncbi.nlm.nih.gov/pubmed/33392515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2643-3230.BCD-20-0132
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