Revealing the Impact of Structural Variants in Multiple Myeloma

The landscape of structural variants (SV) in multiple myeloma remains poorly understood. Here, we performed comprehensive analysis of SVs in a large cohort of 752 patients with multiple myeloma by low-coverage long-insert whole-genome sequencing. We identified 68 SV hotspots involving 17 new candida...

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Publicat a:Blood Cancer Discov
Autors principals: Rustad, Even H., Yellapantula, Venkata D., Glodzik, Dominik, Maclachlan, Kylee H., Diamond, Benjamin, Boyle, Eileen M., Ashby, Cody, Blaney, Patrick, Gundem, Gunes, Hultcrantz, Malin, Leongamornlert, Daniel, Angelopoulos, Nicos, Agnelli, Luca, Auclair, Daniel, Zhang, Yanming, Dogan, Ahmet, Bolli, Niccolò, Papaemmanuil, Elli, Anderson, Kenneth C., Moreau, Philippe, Avet-Loiseau, Hervé, Munshi, Nikhil C., Keats, Jonathan J., Campbell, Peter J., Morgan, Gareth J., Landgren, Ola, Maura, Francesco
Format: Artigo
Idioma:Inglês
Publicat: American Association for Cancer Research 2020
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7774871/
https://ncbi.nlm.nih.gov/pubmed/33392515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2643-3230.BCD-20-0132
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