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Structural alterations within native amyloidogenic immunoglobulin light chains

Amyloid diseases are characterized by the misfolding of a precursor protein that leads to amyloid fibril formation. Despite the fact that there are different precursors, some commonalities in the misfolding mechanism are thought to exist. In light chain amyloidosis (AL), the immunoglobulin light cha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Randles, Edward G., Thompson, James R., Martin, Douglas J., Ramirez-Alvarado, Marina
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840394/
https://ncbi.nlm.nih.gov/pubmed/19361523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.04.010
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