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Structural alterations within native amyloidogenic immunoglobulin light chains

Amyloid diseases are characterized by the misfolding of a precursor protein that leads to amyloid fibril formation. Despite the fact that there are different precursors, some commonalities in the misfolding mechanism are thought to exist. In light chain amyloidosis (AL), the immunoglobulin light cha...

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Detalhes bibliográficos
Main Authors: Randles, Edward G., Thompson, James R., Martin, Douglas J., Ramirez-Alvarado, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840394/
https://ncbi.nlm.nih.gov/pubmed/19361523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.04.010
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