Cytotoxicity of amyloidogenic immunoglobulin light chains in cell culture

Light-chain amyloidosis (AL) is a devastating protein-misfolding disease characterized by abnormal proliferation of plasma cells in the bone marrow that secrete monoclonal immunoglobulin light chains that misfold and form amyloid fibrils, thus causing organ failure and death. Numerous reports on dif...

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Detaylı Bibliyografya
Asıl Yazarlar: Sikkink, L A, Ramirez-Alvarado, M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2010
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032327/
https://ncbi.nlm.nih.gov/pubmed/21368874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2010.75
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