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Cytotoxicity of amyloidogenic immunoglobulin light chains in cell culture
Light-chain amyloidosis (AL) is a devastating protein-misfolding disease characterized by abnormal proliferation of plasma cells in the bone marrow that secrete monoclonal immunoglobulin light chains that misfold and form amyloid fibrils, thus causing organ failure and death. Numerous reports on dif...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3032327/ https://ncbi.nlm.nih.gov/pubmed/21368874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2010.75 |
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