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Role of mutations in the cellular internalization of amyloidogenic light chains into cardiomyocytes

Light chain (AL) amyloidosis is characterized by the misfolding of immunoglobulin light chains, accumulating as amyloid fibrils in vital organs. Multiple reports have indicated that amyloidogenic light chains internalize into a variety of cell types, but these studies used urine-derived proteins wit...

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Podrobná bibliografie
Hlavní autoři: Levinson, Rebecca T., Olatoye, Oludare O., Randles, Edward G., Howell, Kyle G., DiCostanzo, Ara Celi, Ramirez-Alvarado, Marina
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575045/
https://ncbi.nlm.nih.gov/pubmed/23417147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01278
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