Targeted disruption of the CREB coactivator Crtc2 increases insulin sensitivity

Under fasting conditions, increases in circulating concentrations of pancreatic glucagon maintain glucose homeostasis through induction of gluconeogenic genes by the CREB coactivator CRTC2. Hepatic CRTC2 activity is elevated in obesity, although the extent to which this cofactor contributes to atten...

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Detaylı Bibliyografya
Asıl Yazarlar: Wang, Yiguo, Inoue, Hiroshi, Ravnskjaer, Kim, Viste, Kristin, Miller, Nina, Liu, Yi, Hedrick, Susan, Vera, Liliana, Montminy, Marc
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2010
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840317/
https://ncbi.nlm.nih.gov/pubmed/20133702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914897107
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