CREB coactivators CRTC2 and CRTC3 modulate bone marrow hematopoiesis

Populations of circulating immune cells are maintained in equilibrium through signals that enhance the retention or egress of hematopoietic stem cells (HSCs) from bone marrow (BM). Prostaglandin E2 (PGE2) stimulates HSC renewal and engraftment through, for example, induction of the cAMP pathway. Tri...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kim, Jeong-Ho, Hedrick, Susan, Tsai, Wen-Wei, Wiater, Ezra, Le Lay, John, Kaestner, Klaus H., Leblanc, Mathias, Loar, Andrew, Montminy, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676928/
https://ncbi.nlm.nih.gov/pubmed/29078378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712616114
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