CREB coactivators CRTC2 and CRTC3 modulate bone marrow hematopoiesis

Populations of circulating immune cells are maintained in equilibrium through signals that enhance the retention or egress of hematopoietic stem cells (HSCs) from bone marrow (BM). Prostaglandin E2 (PGE2) stimulates HSC renewal and engraftment through, for example, induction of the cAMP pathway. Tri...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Kim, Jeong-Ho, Hedrick, Susan, Tsai, Wen-Wei, Wiater, Ezra, Le Lay, John, Kaestner, Klaus H., Leblanc, Mathias, Loar, Andrew, Montminy, Marc
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2017
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676928/
https://ncbi.nlm.nih.gov/pubmed/29078378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712616114
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