CREB coactivators CRTC2 and CRTC3 modulate bone marrow hematopoiesis

Populations of circulating immune cells are maintained in equilibrium through signals that enhance the retention or egress of hematopoietic stem cells (HSCs) from bone marrow (BM). Prostaglandin E2 (PGE2) stimulates HSC renewal and engraftment through, for example, induction of the cAMP pathway. Tri...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Kim, Jeong-Ho, Hedrick, Susan, Tsai, Wen-Wei, Wiater, Ezra, Le Lay, John, Kaestner, Klaus H., Leblanc, Mathias, Loar, Andrew, Montminy, Marc
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676928/
https://ncbi.nlm.nih.gov/pubmed/29078378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712616114
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