Hepatic Insulin Resistance Following Chronic Activation of the CREB Coactivator CRTC2

Under fasting conditions, increases in circulating concentrations of glucagon maintain glucose homeostasis via the induction of hepatic gluconeogenesis. Triggering of the cAMP pathway in hepatocytes stimulates the gluconeogenic program via the PKA-mediated phosphorylation of CREB and dephosphorylati...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Hogan, Meghan F., Ravnskjaer, Kim, Matsumura, Shigenobu, Huising, Mark O., Hull, Rebecca L., Kahn, Steven E., Montminy, Marc
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2015
Onderwerpen:
Metabolism
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646253/
https://ncbi.nlm.nih.gov/pubmed/26342077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.679266
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items