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Complete Genetic Correction of iPS Cells From Duchenne Muscular Dystrophy

Human artificial chromosome (HAC) has several advantages as a gene therapy vector, including stable episomal maintenance that avoids insertional mutations and the ability to carry large gene inserts including the regulatory elements. Induced pluripotent stem (iPS) cells have great potential for gene...

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Main Authors: Kazuki, Yasuhiro, Hiratsuka, Masaharu, Takiguchi, Masato, Osaki, Mitsuhiko, Kajitani, Naoyo, Hoshiya, Hidetoshi, Hiramatsu, Kei, Yoshino, Toko, Kazuki, Kanako, Ishihara, Chie, Takehara, Shoko, Higaki, Katsumi, Nakagawa, Masato, Takahashi, Kazutoshi, Yamanaka, Shinya, Oshimura, Mitsuo
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2009
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839293/
https://ncbi.nlm.nih.gov/pubmed/19997091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.274
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