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Endoplasmic reticulum stress and the unfolded protein response are linked to synergistic IFN-β induction via XBP-1

Type I IFN are strongly induced upon engagement of certain pattern recognition receptors (PRR) by microbial products, and play key roles in regulating innate and adaptive immunity. It has become apparent that the endoplasmic reticulum (ER) stress-induced unfolded protein response (UPR), in addition...

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Bibliographische Detailangaben
Hauptverfasser: Smith, Judith A., Turner, Matthew J., DeLay, Monica L., Klenk, Erin I., Sowders, Dawn P., Colbert, Robert A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838478/
https://ncbi.nlm.nih.gov/pubmed/18412159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200737882
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