Endoplasmic reticulum stress and the unfolded protein response are linked to synergistic IFN-β induction via XBP-1

Type I IFN are strongly induced upon engagement of certain pattern recognition receptors (PRR) by microbial products, and play key roles in regulating innate and adaptive immunity. It has become apparent that the endoplasmic reticulum (ER) stress-induced unfolded protein response (UPR), in addition...

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Main Authors: Smith, Judith A., Turner, Matthew J., DeLay, Monica L., Klenk, Erin I., Sowders, Dawn P., Colbert, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838478/
https://ncbi.nlm.nih.gov/pubmed/18412159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200737882
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