XBP-1 couples endoplasmic reticulum stress to augmented IFN-β induction via a cis-acting enhancer in macrophages

Perturbation of the endoplasmic reticulum (ER) results in a conserved stress response called the “Unfolded Protein Response” (UPR). Macrophages undergoing a UPR respond to LPS with log-fold increased production of IFN-β, a cytokine with diverse roles in innate and adaptive immunity. In this report,...

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Bibliographic Details
Main Authors:	Zeng, Ling, Liu, Yi-Ping, Sha, Haibo, Chen, Hui, Qi, Ling, Smith, Judith A.
Format:	Artigo
Language:	Inglês
Published:	2010
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2916979/ https://ncbi.nlm.nih.gov/pubmed/20660350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903052
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XBP-1 couples endoplasmic reticulum stress to augmented IFN-β induction via a cis-acting enhancer in macrophages

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