XBP-1 couples endoplasmic reticulum stress to augmented IFN-β induction via a cis-acting enhancer in macrophages

Perturbation of the endoplasmic reticulum (ER) results in a conserved stress response called the “Unfolded Protein Response” (UPR). Macrophages undergoing a UPR respond to LPS with log-fold increased production of IFN-β, a cytokine with diverse roles in innate and adaptive immunity. In this report,...

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Detaylı Bibliyografya
Asıl Yazarlar: Zeng, Ling, Liu, Yi-Ping, Sha, Haibo, Chen, Hui, Qi, Ling, Smith, Judith A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916979/
https://ncbi.nlm.nih.gov/pubmed/20660350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903052
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