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Flavivirus Infection Activates the XBP1 Pathway of the Unfolded Protein Response To Cope with Endoplasmic Reticulum Stress

The unfolded protein response (UPR) is a coordinated change in gene expression triggered by perturbations in functions of the endoplasmic reticulum (ER). XBP1, a key transcription factor of the UPR, is activated by an IRE1-mediated splicing event, which results in a frameshift and encodes a protein...

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Main Authors: Yu, Chia-Yi, Hsu, Yun-Wei, Liao, Ching-Len, Lin, Yi-Ling
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2006
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1642612/
https://ncbi.nlm.nih.gov/pubmed/16987981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00879-06
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